I am just gathering more information from my brother as regard the complications and how he cured this, but he did take matters into his own hands and in a very short time completely healed the Ulcer that was as big as his fist. His condition lasted nearly five years and he was so desperate he even asked doctors to remove his leg. Thats how bad the discomfort was. This is a picture from the internet but it does represent what it looks like. This could take me some time to put together, so if you are suffering from Pyoderma-gangrenosum and you absolutely have had enough with drugs and potions that dont seem to be working, please get in touch and ill get my brother to touch base with you. For now, Take care. Your not alone. Peter